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PCAT Practice Questions | Answers and Explanations

1. A
Enzymes are protein catalysts that increase the rate of a reaction by reducing the activation energy necessary for it to proceed. Activation energy is defined as the minimum amount of energy required for a reaction to occur.

Before we examine the other answer choices, let's discuss reaction thermodynamics. All chemical reactions are accompanied by energy changes. These energy changes are described by a function – Gibbs free energy (G) – that denotes the energy of a system available to do work. The change in free energy (deltaG) for a given reaction can be determined from the equation ΔH - TΔS, where ΔH is the change in enthalpy (heat absorbed or evolved by the system), T is the absolute temperature, and ΔS is the change in entropy (degree of randomness).

During the course of an enzyme-catalyzed reaction, ΔG does not change. Thus, according to the above equation, ΔH and ΔS do not change either, so choices B and C are incorrect. Choice D is incorrect because an enzyme does not change the energy state of either the reactants or the products of a reaction—it works by producing more favorable reaction kinetics, which results in lowering the activation energy.

2. C
This is a "probability" genetics question that can be answered by practical application of Mendel's Laws. Mendel's Law of Segregation states that alleles segregate during meiosis, resulting in gametes that carry only one allele for any given inherited trait (i.e., haploid gametes). Mendel's Law of Independent Assortment states that unlinked genes assort independently during meiosis. By applying Mendel's Laws, we can conclude that each parent in the problem can produce two possible gametes. The father can produce the gametes GH and gH, and the mother can produce the gametes gH and gh. The probability of the father's genotype (GgHH) appearing in the progeny can be determined by calculating the number of different gamete combinations that will produce this genotype. Thus, a GgHH zygote can only be produced by the fusion of a GH gamete and a gH gamete.

The probability that one parent will donate a particular gamete is independent of the probability that the other parent will donate a particular gamete. Thus, the probability of the father donating a GH gamete is =, and the probability of the mother donating a gH gamete is =. The probability of producing a genotype that requires the occurrence of both these independent events is equal to the product of the individual probabilities that these events will occur. Thus = x = = <, so the probability that this couple will have a child with the genotype GgHH is <, or choice C.

3. B
The thylakoid sacs contain chlorophyll, the photopigment that absorbs light in photosynthesis. They are arranged in columns.

4. B
Only ionic compounds (electrolytes) dissolved in polar solvents will conduct electricity. Sugar is a covalent solid, and therefore is not an electrolyte even when dissolved in water. Answers (C) and (D) are incorrect because salt will not dissolve appreciably in an organic solvent, and oil and water are immiscible. NaCl is an ionic compound, so (B) is correct.

5. A
Here's a question where you might look for answer choices that are functionally similar to the words in the stem pair. In the stem pair, to FILTER is to remove the IMPURITY from something. To filter water, for instance, means to remove dirt and sediment from it. Analogously, to expurgate is to remove the obscenity from something, usually a piece of writing. (B) doesn't fit the bridge because to whitewash is "to cover up." In (C), perjury is lying during testimony, when you've sworn to tell the truth.

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6. C
In one mole of NaOH, there are one mole of sodium, one mole of oxygen and one mole of hydrogen. Because the molar masses of sodium, oxygen, and hydrogen are 23 g/mol, 16 g/mol, and 1 g/mol, respectively, there are 16 g of oxygen, 23 g of sodium, and 1 g of hydrogen in one mole of sodium hydroxide. Therefore, the percent composition by mass of oxygen in sodium hydroxide is equal to the mass of one mole of oxygen, 16 g, divided by the mass of one mole of sodium hydroxide (23+16+1) multiplied by 100. This is equal to 16/40 X 100—40%.

7. C
Erythrocytes (red blood cells) are formed in the bone marrow, where they lose their nuclei, mitochondria, and membranous organelles.

Choices (A), (B), and (D) are all incorrect because they refer to cells that contain nuclei.

8. D
The first thing that you must do is find out how much each sale item costs (90/6 = 15 cents). To find how much you save per package, subtract from the normal price (19 cents) the sale price (15 cents). The total savings is 4 cents per package. 4 cents times 24 packages = 96 cents.

9. B
The easiest way to find a in this question is to add the equations together. 2a + 4a = 6a, -b + b = 0, and 1 + 17 = 18, so you're left with 6a = 18. Dividing both sides by 6 gives you a = 3.

10. B
Note that the two words in the stem pair are tough opposites. If you PARAPHRASE something, it, by definition, will not be VERBATIM, or word for word. Likewise, if you estimate something, by definition, it will not be precise.

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